Toradol (Ketorolac)

What is Toradol?

Toradol (ketorolac) is a nonsteroidal anti-inflammatory drug (NSAID). Ketorolac works by reducing hormones that cause inflammation and pain in the body.

Toradol is used short-term (5 days or less) to treat moderate to severe pain.

Toradol may also be used for purposes not listed in this medication guide.

Important information

You should not use Toradol if you have any active or recent bleeding (including bleeding inside your body), a head injury, a stomach ulcer, severe kidney disease, a bleeding or blood-clotting disorder, a history of severe allergic reaction to aspirin or an NSAID, or if you are scheduled to have surgery.

Do not use Toradol if you are in your third trimester of pregnancy or if you are breast-feeding a baby.

You should not use Toradol if you also take pentoxifylline, probenecid, aspirin, or other NSAID drugs (which may include ibuprofen, acetaminophen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, and others and others).

Toradol can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Toradol may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Toradol, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.

Do not drink alcohol while taking Toradol. Alcohol can increase the risk of stomach bleeding caused by ketorolac.

Before taking this medicine

Toradol can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.

Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

You should not use Toradol if you are allergic to ketorolac, or if you have:

  • active or recent stomach ulcer, stomach bleeding, or intestinal bleeding;

  • a bleeding or blood-clotting disorder;

  • a closed head injury or bleeding in your brain;

  • bleeding from a recent surgery;

  • severe kidney disease or dehydration;

  • a history of asthma or a severe allergic reaction after taking aspirin or an NSAID;

  • if you are scheduled to have surgery (especially bypass surgery); or

  • if you are in the third trimester of pregnancy or breast-feeding a baby.

Some medicines can cause unwanted or dangerous effects when used with Toradol. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • pentoxifylline;

  • probenecid; or

  • aspirin or other NSAIDs - ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

To make sure Toradol is safe for you, tell your doctor if you have ever had:

  • heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;

  • heart attack, stroke, or blood clot;

  • stomach ulcers or bleeding;

  • inflammatory bowel disease, ulcerative colitis, or Crohn's disease;

  • liver disease;

  • kidney disease (or if you are on dialysis);

  • asthma; or

  • fluid retention.

Using Toradol during the last 3 months of pregnancy may harm the unborn baby. Ketorolac may also increase the risk of uterine bleeding and is not for use during labor and delivery. Tell your doctor if you are pregnant.

Ketorolac can pass into breast milk and may harm a nursing baby. Do not breast-feed while using this medicine.

Toradol is not approved for use by anyone younger than 2 years old.

What should I avoid while taking Toradol?

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Ask a doctor or pharmacist before using any cold, allergy, or pain medication. Many medicines available over the counter contain aspirin or other medicines similar to Toradol. Taking certain products together can cause you to get too much of this type of medication. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, or naproxen.

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